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Feigelson HS, Patel AV, Teras LR, Gansler T, Thun MJ, Calle EE. Adult weight gain and histopathologic characteristics of breast cancer among postmenopausal women. Cancer. 2006 Jul 1;107(1):12-21.
The Cancer Project News, Fall 2006
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More evidence shows that being overweight increases a woman’s
risk for breast cancer. The relationship between weight gain and
a type of invasive breast cancer among 44,161 postmenopausal women was examined
by a group of scientists at the American Cancer Society. Women
with over 60 pounds of adult weight gain were nearly two times as likely
as women with 20 pounds or less of adult weight gain to develop one form
of breast cancer. Weight gain was associated with increased risk for all
types, stages, and grades of breast cancer, particularly advanced cases.
Obese women were three times as likely to develop regional or distant metastases
compared with women who had minimal weight gain in adulthood. This study
emphasizes the importance of maintaining a healthy weight throughout life.